Antioxidant and antiradical activities of L-carnitine. Gülçin, I. Life Sciences 78(8): L-carnitine plays an important regulatory role in the. Antioxidant and antiradical activities of l-carnitine. I˙lhami Gьlзin *. Atatьrk University, Faculty of Arts and Sciences, Department of Chemistry, TR Erzurum-. L-carnitine plays an important regulatory role in the mitochondrial transport of long-chain free fatty acids. In this study, the antioxidant activity of L-carnitine was .

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Oxygen toxicology, oxygen radicals, transition metals and disease.

At different concentrations, l-carnitine showed an effective reducing power Fig. Blank solution was containing the phosphate buffer without H2O2. As can be seen in Fig. Anturadical of color reduction therefore allows estimating the metal chelating activity of the coexisting chelator.

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Metal chelating capacity was significant since it reduced the concentration of the catalysing transition metal in lipid peroxidation. Antioxidative actiities of oolong tea.

Acetyl-lcarnitine corrects the altered peripheral nerve function of experimental diabetes. Antioxidant activity of water extract of harng jyur Chrysanthemum morifolium Ramat. A solution of H2O2 40 mM was prepared in phosphate buffer pH 7.

The reaction mixture was incubated at 25 -C for 5 min and the absorbance at nm was measured against blank samples. Asian Journal of Chemistry 17 1— Journal of Neuroscience Research 66, — By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy PolicyAdn of Serviceand Dataset License.

Antioxidant and antiradical activities of L-carnitine

International Pediatry 5, — In anf, lcarnitine treatment has been found to be able to elevate ppar. In addition, l-carnitine had an effective DPPHI scavenging, superoxide anion radical scavenging, hydrogen peroxide scavenging, total reducing power and metal chelating on ferrous ions activities. Studies on the antioxidative activities of Hsian-tsao Mesona procumbens Hemsl leaf gum. An abstraction of a hydrogen atom from C-2 may be occurred easily.


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This paper has highly influenced 25 other papers. The catalytic decomposition of hydrogen peroxide by iron salts. Molecular mechanism of action of l-carnitine in treatment of myocardial wnd at the experimental levels.

Excessive formation of free radicals accelerates the oxidation of lipids in foods and decreases food quality and consumer acceptance Min, Antioxidant effect of l -carnitine and its short chain esters. Conclusion According to data of the present study, l-carnitine was found to be an effective antioxidant in different in vitro assay including reducing power, DPPH radical and superoxide anion radical scavenging, hydrogen peroxide scavenging and metal chelating activities when it is compared to standard antioxidant compounds such as a-tocopherol, a natural antioxidant, and trolox which is a water-soluble analogue of tocopherol.

Reviews on mechanisms of in vitro antioxidant activity of. It has also been reported that antioxidant properties of some flavonoids are effective mainly via scavenging of superoxide anion radical Yen and Antuoxidant, Comparison between the radical scavenging activity and antioxidant activity of six distilled and nondistilled Mediterranean herbs and aromatic plants.

Journal of Pineal Research 33, — Protection of rat skeletal muscle fibers by either L-carnitine or coenzyme Q10 against statins toxicity mediated by mitochondrial reactive oxygen generation Paolo G. Antioxidant and antiradical activities of Wu Ling Shen in a cell free system. Antioxidant and antiradical activities of l carnitine.

Japanese Journal Nutrition 44, — Despite the low level of h-oxidation in brain, l-carnitine is actively transported antioxiidant the blood — brain barrier and accumulates in neural cells Shug et al. Seventy semen samples 37 asthenozoospermic and 33 normozoospermic were involved in this study.


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Antirzdical of extracted citations. Food and Chemical Toxicology 24, — Academic Press, London, pp. Increased absorbance of the reaction mixture indicates an increase of reduction capability. The inhibition percentage of superoxide anion generation was calculated by using the following formula: Addition of hydrogen peroxide to cells in culture can lead to transition metal iondependent OH radicals mediated oxidative DNA damage.

Pharmacological Research 44, — Marcel Dekker, New York, pp. Antioxidants can protect the antioxidaht body from free radicals and ROS effects and retard the progress of many chronic diseases as well as lipid peroxidation Pryor, ; Kinsella et al. Antiarrhythmic effect of l -carnitine. Superoxide has also been observed to directly initiate lipid peroxidation Wickens, The inhibition percentage of lipid peroxidation in linoleleic acid emulsion was calculated by following equation: Therefore, 5 mL of linoleic acid emulsion contained International Journal Of Food Properties: Antiradical and antioxidant activities of alkaloids isolated from Mahonia aquifolium.

Also, it has been implicated in several pathophysiological processes due to its transformation into more reactive species such as hydroxyl radical that initiate lipid peroxidation. Total phenolic content, antiradical, antioxidant and antimicrobial activities of Rhododendron honeys.

Antioxidant, antiradical and antimutagenic activities of phenolic compounds present in maple products. Lebensmittel Wissenchaft und-Technologie 36, — Among the transition metals, iron is known as the most important lipid oxidation antiradiczl due to its high reactivity.

Antiulcer and in vitro antioxidant activities of Jasminum grandiflorum L.